Congenital lower lip pits and bilateral clefting of the upper lip.
نویسندگان
چکیده
An apparently sporadic case of congenital lower lip pits in association with upper lip bilateral clefts is described in an 11-month-old boy. The presentation, mode of inheritance, aetiology and genetic significance are briefly reviewed.
منابع مشابه
Bilateral Congenital Upper Eyelids Ectropion in Case of Bilateral Cleft Lip and Palate
Purpose: To report a case of bilateral congenital Ectropion and its management. Case Report: A newborn with bilateral congenital upper eyelid Ectropion and sign of exposure keratopathy associated with bilateral cleft lip and palate was referred and underwent full thickness skin graft of both upper eyelids. Ectropion was corrected and sign of exposure keratopathy improved. Conclusion: Congenital...
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Lip pits are a rare congenital anomaly that presents on the upper or lower lip or the commissure of the lips. Lip pits are an autosomal dominant trait occurring almost always in association with cleft lip or palate. They most commonly occur in association with developmental disturbances such as Van der Woude's syndrome, popliteal pterygium syndrome, oro-facial-digital syndrome, Marres-Cremers s...
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Although it is a rare developmental malformation, van der Woude syndrome is the most common form of syndromic orofacial clefting, accounting for approximately 2% of all cleft cases. The lower lip pits with or without a cleft lip or palate is characteristic of the syndrome. Findings, such as hypodontia, limb deformities, popliteal webs, ankylogossia, ankyloblepheron, and genitourinary and cardio...
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Cleft lip or palate and lower lip pits are typical features of the autosomal dominantly inherited Van der Woude syndrome. Limb defects have not been reported in this syndrome so far. A girl with a unilateral complete cleft lip and palate, bilateral lower lip pits, and amniotic deformities of all four limbs is reported and the possibility of chance occurrence of cleft lip and palate, lower lip p...
متن کاملSignaling through Tgf-β type I receptor Alk5 is required for upper lip fusion
Cleft lip with or without cleft palate is one of the most common congenital malformations in newborns. While numerous studies on secondary palatogenesis exist, data regarding normal upper lip formation and cleft lip is limited. We previously showed that conditional inactivation of Tgf-beta type I receptor Alk5 in the ectomesenchyme resulted in total facial clefting. While the role of Tgf-beta s...
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ورودعنوان ژورنال:
- East African medical journal
دوره 71 5 شماره
صفحات -
تاریخ انتشار 1994